Welcome to Labex Recombinant Proteins
Labex Recombinant Proteins is a biomanufacturing company specializing in novel technologies for the production of recombinant proteins for research and diagnostic use. We are dedicated to delivering high-quality products with precision and reliability. Our expert team focuses on advancing innovation to support global scientific and medical communities.
Key Features of our Next-Generation Production Technology
Cutting-Edge Recombinant Protein Production Technology
- Patented E.coli expression platform for high level extra-cellular production of recombinant proteins.
- Large basket of protein products made by this generic technology for research & diagnostic use.
- The proteins are highly pure > 98%.
- Properly folded proteins which exhibit the required biological activity in appropriate cell lines.
- Highly stable products under the defined storage conditions in both liquid & powder form as tested by ELISA.
- Available both with & without carrier proteins.
- Proteins do not contain any extra amino acid at N-terminal like methionine.
Key steps of our production process
Working cell bank storage at -80⸰C
Protein Production at Shake-Flask Level
Buffer-exchange for Polishing of Proteins
Filtration of Supernatant Containing Extracellular Proteins
MBP Purification of Diafiltered Supernatant Containing Recombinant Protein
Analyzing protein gene sequences.
Testing Purified Protein Purity by Silver Staining
Growing & Maintaining Cell Lines for Bio-Assay of Proteins
Microscopy to evaluate growth of cell lines used for bioassay
Diafiltration of Filtered Supernatant Containing Extracellular Protein
REFERNCES
- Sharma, A.K., Shukla, E., Janoti, D.S. et al. A novel knock-out strategy to enhance recombinant protein expression in Escherichia coli. Microb Cell Fact 19, 148 (2020). Read More
- Ghosh, C., Gupta, R. & Mukherjee, K.J. An inverse metabolic engineering approach for the design of an improved host platform for over-expression of recombinant proteins in Escherichia coli. Microb Cell Fact 11, 93 (2012). Read More
- Mahalik, S., Sharma, A.K. & Mukherjee, K.J. Genome engineering for improved recombinant protein expression in Escherichia coli. Microb Cell Fact 13, 177 (2014). Read More
- Guleria, R., Jain, P., Verma, M. et al. Designing next generation recombinant protein expression platforms by modulating the cellular stress response in Escherichia coli. Microb Cell Fact 19, 227 (2020). Read More
- Bhattacharya, P., Pandey, G., Srivastava, P. et al. Combined effect of protein fusion and signal sequence greatly enhances the production of recombinant human GM-CSF in Escherichia coli . Mol Biotechnol 30, 103–115 (2005). Read More